Closed-Loop Insulin Delivery in Type 1 Diabetes
نویسندگان
چکیده
منابع مشابه
Closed-loop insulin delivery for treatment of type 1 diabetes
Type 1 diabetes is one of the most common endocrine problems in childhood and adolescence, and remains a serious chronic disorder with increased morbidity and mortality, and reduced quality of life. Technological innovations positively affect the management of type 1 diabetes. Closed-loop insulin delivery (artificial pancreas) is a recent medical innovation, aiming to reduce the risk of hypogly...
متن کاملSimulation environment to evaluate closed-loop insulin delivery systems in type 1 diabetes.
BACKGROUND Closed-loop insulin delivery systems linking subcutaneous insulin infusion to real-time continuous glucose monitoring need to be evaluated in humans, but progress can be accelerated with the use of in silico testing. We present a simulation environment designed to support the development and testing of closed-loop insulin delivery systems in type 1 diabetes mellitus (T1DM). METHODS...
متن کاملClosed-Loop Basal Insulin Delivery Over 36 Hours in AdolescentsWith Type 1 Diabetes Randomized clinical trial
RESEARCH DESIGN AND METHODSdTwelve adolescents with type 1 diabetes (five males; mean age 15.0 [SD 1.4] years; HbA1c 7.9 [0.7]%; BMI 21.4 [2.6] kg/m ) were studied at a clinical research facility on two occasions and received, in random order, either closed-loop basal insulin delivery or conventional pump therapy for 36 h. During closed-loop insulin delivery, pump basal rates were adjusted ever...
متن کاملClosed-Loop Basal Insulin Delivery Over 36 Hours in Adolescents With Type 1 Diabetes
OBJECTIVE We evaluated the safety and efficacy of closed-loop basal insulin delivery during sleep and after regular meals and unannounced periods of exercise. RESEARCH DESIGN AND METHODS Twelve adolescents with type 1 diabetes (five males; mean age 15.0 [SD 1.4] years; HbA1c 7.9 [0.7]%; BMI 21.4 [2.6] kg/m(2)) were studied at a clinical research facility on two occasions and received, in rand...
متن کاملClosed-Loop Insulin Delivery During Pregnancy Complicated by Type 1 Diabetes
OBJECTIVE This study evaluated closed-loop insulin delivery with a model predictive control (MPC) algorithm during early (12-16 weeks) and late gestation (28-32 weeks) in pregnant women with type 1 diabetes. RESEARCH DESIGN AND METHODS Ten women with type 1 diabetes (age 31 years, diabetes duration 19 years, BMI 24.1 kg/m(2), booking A1C 6.9%) were studied over 24 h during early (14.8 weeks) ...
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ژورنال
عنوان ژورنال: Endocrinology and Metabolism Clinics of North America
سال: 2012
ISSN: 0889-8529
DOI: 10.1016/j.ecl.2011.12.003